Acute hypoglycemic, hypocholesterolemic and hypotriglyceridemic effects

Pakistan is rich in medicinally important plants and has ancient herbal treatment methods. Present work is based on the study of six indigenous plants Eugenia jambolana, Lawsonia inermis, Momordica charantia, Morus Corresponding author: Tel.: +92-21-4610132; E-mail [email protected] M. Saeed Arayne et al. Pak. J. Pharm. Sci., 2007, Vol.20(4), 268-273 269 alba, Nigella sativa and Trigonella foenum graecum which show the inhibitory effect of glucose utilization, and are in use as hypoglycemic agents of varying degree in traditional system of medicine. The glucose uptake activity of (methanolic extracts) of these plants was tested in vitro and glucose was estimated by glucose oxidase method. The results in three different media revealed that, hypoglycemic activity is more prominent in neutral and basic media as compared to acidic medium.